Panama Canal 20 days from New York to San Francisco

Day 1

New York

Departure: 16:00

New York – the city that never sleeps

From the Empire State Building to Lady Liberty and Times Square, New York is a global icon. Beyond sightseeing, it’s a hub for dining, shopping, arts, culture, and nightlife.

Explore world-famous landmarks, stroll along Fifth Avenue, marvel at the Chrysler Building, and enjoy the skyline from the Empire State or Statue of Liberty.

Each neighbourhood has its own vibe: SoHo and Chelsea for cafés, bars, and boutiques; Upper Manhattan for Harlem and Little Dominican Republic; Hell’s Kitchen for iconic restaurants.

For a quieter, greener side, head to Greenwich Village or escape into Central Park, the perfect oasis in Manhattan.

With TUI, you can also book tickets to sports and music events, making your New York experience even more unforgettable.

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Day 4

puerto plata, dominican rep

Arrival: 10:00 - Departure: 18:00

Puerto Plata

Discover the charm of Puerto Plata, a vibrant city on the northern coast of the Dominican Republic. Known for its golden sandy beaches and welcoming people, it’s the perfect place to combine relaxation, culture, and adventure. Stroll through colorful local markets, enjoy the lively seafront promenade, and soak up the warm Caribbean atmosphere.

Take the cable car to the top of the mountain behind the city, where you’ll find an impressive replica of Rio de Janeiro’s Christ the Redeemer. Along the way, enjoy panoramic viewpoints, a small cave, and a lagoon perfect for photos. History lovers will enjoy Fortaleza San Felipe, a historic fort by the bay surrounded by a lovely green area ideal for a picnic with sea views.

Whether you want to relax on the beach, explore local culture, or enjoy spectacular scenery, Puerto Plata offers an unforgettable Caribbean experience.

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Day 6

cartagena, colombia

Arrival: 12:00 - Departure: 19:00

Declared part of the UNESCO World Heritage in 1984, Cartagena de Indias is quite possibly one of South America's most beautiful city. Facing the Caribbean Sea to the west with Cartagena Bay to the south, the city is Colombia's top travel attraction. The city encapsulates all the charm of Spanish colonial architecture. The old town of Cartagena is immaculately preserved, with numerous beautiful plazas, churches and old buildings to marvel at. Walking down its picture-perfect streets is just a delight. Stroll along an enchanting maze of cobbled alleys and admire the Spanish colonial buildings including the Palace of the Inquisition, the Clock-Tower and the Castle of San Felipe de Barajas. Eating out is another form of entertainment in Cartagena, with countless choices of new and exotic flavours in its local and international restaurants. Cartagena offers all the enchantment of its history and it is considered one of the greatest cultural treasures in the Americas.

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Day 7

colon (cristobal), panama

Arrival: 11:30 - Departure: 22:00

Colón is a sea port on the Caribbean Sea coast of Panama. It is the capital of Panama's Colón Province and has traditionally been known as Panama's second city. MAIN TOURIST ATTRATIONS • Parks and Statues. The most notable is the one you see coming into Colón on Central Ave. • Christ Church by the Sea • Colón 2000, Paseo Gorgas. • Columbus Cathedral. Beautiful Catholic church that's worth a picture, but don't leave the taxi and walk around there. • Gatún Locks, Panama Canal.

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Day 8

panama canal (cruising)

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Day 10

caldera, costa rica

Arrival: 07:00 - Departure: 18:00

San Jose, the capital of Costa Rica, has a very different vibe than most of Latin America with a lot more American influenced architecture and a Mediterranean climate. San Jose is a town in the middle of nature. Located in the Central Valley, the city is surrounded by the most varied forms of wildlife as well as the volcanos, Poás and Irazú. It is also the central point from where you can reach the country’s rich National Parks, its gorgeous beaches, its amazing rivers and its pristine mountains.San José has certain attraction on its own like the National Theatre, the Central Market, the National Museum or the Metropolitan Cathedral. Moreover, its friendly people give a lively vibe to the city, something you can appreciate in the city’s many restaurants and bars. Some museums and buildings give away their colonial past and European artistic influences. San Jose also has much to offer and it is a city of great historical and cultural significance.

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Day 12

puerto quetzal,guatamala

Arrival: 07:00 - Departure: 18:00

Monterrico is a coastal town facing the Pacific Ocean in the south of Guatemala's Santa Rosa department. It is located in the activity center of the Monterrico Nature Reserve. This area is popularly known for its peculiar black volcanic sand beaches and for the large influx of sea turtles on the coast.

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Day 14

acapulco, mexico

Arrival: 07:00 - Departure: 17:00

Acapulco, with stunning white-sand luxury beaches and a 24-hour nightlife, is a popular holiday destination located on the gorgeous Bahía de Acapulco. There are plenty of reasons to visit this beautiful port city and there is something for everyone. The water, of course, isn't the only incredible feature of this picturesque top travel destination. There's plenty to do and see on land, too. Golf lovers will find lots of places to practice their stroke and tennis enthusiasts can work on their serve or backhand while on their Acapulco vacation. Adults aren't the only ones who will love Acapulco. This kid-friendly destination loves children and resorts do everything possible to make them feel at home. Children will enjoy the sandy white beaches as well as Acapulco's other interesting attractions including a large number of , water parks, amusement areas, lush green parks, an aquarium, and even a roller skating rink. History fanatics will want to sign up for a guided history tour of the city, which includes stops at landmarks such as the Chapel of Peace, Fort San Diego, and the old Flamingo Hotel, frequented long ago by the rich and famous. Gourmets will never be disappointed here. The restaurants in Acapulco are varied and extraordinary, offering a wide range of international cuisine and exquisite local food. In the evenings, Acapulco literally sparkles. Its reputation as a thrilling party town is legendary. Don’t miss out, there are no grumpy faces here!

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Day 16

cabo san lucas, mexico

Arrival: 07:00 - Departure: 14:00

Los Cabos, at the southern tip of Mexico’s Baja California Peninsula, is where desert, mountains, and the Pacific Ocean meet in dramatic fashion. The region is anchored by two main towns: lively Cabo San Lucas, famous for its nightlife and marina, and the more laid‑back San José del Cabo, known for colonial architecture and art galleries. Between them stretches the “Tourist Corridor,” a scenic coastal highway lined with luxury resorts, golf courses, and pristine beaches. Most visitors are drawn to the sea. Boat tours take you past the iconic El Arco rock formation at Land’s End, where the Sea of Cortez meets the Pacific, and offer chances to spot sea lions, dolphins, and in season, migrating humpback and gray whales. Snorkeling and diving reveal colorful reefs and abundant marine life at spots like Santa Maria Bay and Chileno Bay, while adventurers can try deep‑sea fishing, surfing, kitesurfing, or stand‑up paddleboarding. On land, Los Cabos offers a surprising variety of landscapes and activities. You can ride camels or ATVs through cactus‑studded desert, zip‑line across canyons, or hike in the Sierra de la Laguna mountains, a UNESCO Biosphere Reserve with freshwater pools and oak forests. Several world‑class golf courses overlook the ocean, and horseback rides at sunset along the beach are a romantic favorite. Food and culture add another layer to the experience. Los Cabos blends traditional Mexican flavors with fresh seafood and sophisticated coastal cuisine, from street‑side tacos al pastor to upscale farm‑to‑table restaurants in the nearby village of El Pescadero. Evenings can be spent bar‑hopping around Cabo San Lucas’s marina, enjoying live music and beach clubs, or strolling the Art Walk in San José del Cabo’s historic center, where galleries, boutiques, and cafés stay open late.

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Day 19

san francisco, california

Arrival: 09:00

San Francisco is a major, lively and cosmopolitan city in California. In San Francisco, history and modernity combine to give visitors an unforgettable experience. From Mission Dolores, the city's first stone building or the city’s legendary cable cars to the high-tech Financial District. A trip to San Francisco is bound to leave you with incredible memories. A boat trip is a great way to explore the “City by the Bay.” Explore Fisherman's Wharf, full of shops, galleries and restaurant offering delicious seafood. Stroll down the Golden Gate and admire the views over the bay and the Pacific Ocean, visit the various maritime museums, and , of course, no visit to San Francisco is complete without an excursion to Alcatraz, the island prison that once held some of the country’s most notorious criminals, such as Al Capone. If it’s a more relaxed environment you’re after, pass through the stately architecture and flowing lagoon of the Palace of Fine Arts. The Transamerica Pyramid has become the city's most famous landmark. The 260 metre high pyramid structure is situated in the heart of the Financial District. Located between three hills, San Francisco's Chinatown is the largest Chinese settlement outside Asia with pagodas, colourful bunting, decorated balconies and Chinese characters combining with the sounds and exotic aromas of this fascinating area. The Painted Ladies are charming Victorian wooden houses situated on the fringe of Alamo Square and the Haas-Lilienthal House is a well-maintained jewel of a bygone era. San Francisco thrives on variety and has a contagious energy. This city is magical and everyone should come here at least once.

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Day 20

san francisco, california

San Francisco is a major, lively and cosmopolitan city in California. In San Francisco, history and modernity combine to give visitors an unforgettable experience. From Mission Dolores, the city's first stone building or the city’s legendary cable cars to the high-tech Financial District. A trip to San Francisco is bound to leave you with incredible memories. A boat trip is a great way to explore the “City by the Bay.” Explore Fisherman's Wharf, full of shops, galleries and restaurant offering delicious seafood. Stroll down the Golden Gate and admire the views over the bay and the Pacific Ocean, visit the various maritime museums, and , of course, no visit to San Francisco is complete without an excursion to Alcatraz, the island prison that once held some of the country’s most notorious criminals, such as Al Capone. If it’s a more relaxed environment you’re after, pass through the stately architecture and flowing lagoon of the Palace of Fine Arts. The Transamerica Pyramid has become the city's most famous landmark. The 260 metre high pyramid structure is situated in the heart of the Financial District. Located between three hills, San Francisco's Chinatown is the largest Chinese settlement outside Asia with pagodas, colourful bunting, decorated balconies and Chinese characters combining with the sounds and exotic aromas of this fascinating area. The Painted Ladies are charming Victorian wooden houses situated on the fringe of Alamo Square and the Haas-Lilienthal House is a well-maintained jewel of a bygone era. San Francisco thrives on variety and has a contagious energy. This city is magical and everyone should come here at least once.

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Panama Canal 20 days from New York to San Francisco

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